Publications

MITOCHONDRIAL MEMBRANES LAB.

Check out our complete list of publications!

2023

Small, 2307045

C60‐based Multivalent Glycoporphyrins Inhibit SARS‐CoV‐2 Specific Interaction with the DC‐SIGN Transmembrane Receptor.

Patino‐Alonso J, Cabrera‐González J *, Merino J, Nieto‐Ortiz G, Lasala F, Katati J, Bezerra da Cruz CH, Monnappa AK, Mateos‐Gil P, Canales A*, López‐Montero I*, M Illescas B*, Delgado R*, Martín N*

npj Biofilms and Microbiomes 9, 92

Expansion microscopy applied to mono-and dual-species biofilms.

Valdivieso González D, Jara J, Almendro-Vedia VG, Orgaz G, López-Montero I.

Advanced Science 10, 2301606

Rotation of the c-Ring Promotes the Curvature Sorting of Monomeric ATP Synthases.

Valdivieso González D, Makowski M, Lillo MP, Cao‐García FJ, Melo MN, Almendro‐Vedia VG, López‐Montero I.

iScience 26, 107004

Activity modulation of the Escherichia coli F1FO ATP synthase by a designed antimicrobial peptide via cardiolipin sequestering.

Makowski M, Almendro-Vedia VG, Domingues MM, Franco OL, López-Montero I*, Melo MN*, Santos NC*.

Bioelectrochemistry 152, 108432.

Electro-enzymatic ATP regeneration coupled to biocatalytic phosphorylation reactions.

García-Molina G, Natale P, Coito AM, Cava DG, Pereira IAC, López-Montero I, Vélez M, Pita M, De Lacey AL.

The Journal of Chemical Physics 158, 074902

Rheology of Pseudomonas fluorescens biofilms: From experiments to predictive DPD mesoscopic modeling.

Martín-Roca J, Bianco V, Alarcón F, Monnappa AK, Natale P, Monroy F, Orgaz B, López-Montero I, Valeriani C.

Organic Chemistry Frontiers 10, 5834-5842

Dissimilar-at-boron N-BODIPYs: from light-harvesting multichromophoric arrays to CPL-bright chiral-at-boron BODIPYs.

Ray C, Avellanal-Zaballa E, Muñoz-Úbeda M, Colligan J, Moreno F, Muller G, López-Montero I, Bañuelos J, Maroto BL, de la Moya S.

Journal of Materials Chemistry B 11: 2108-2114

Polar ammoniostyryls easily converting a clickable lipophilic BODIPY in an advanced plasma membrane probe.

Serrano-Buitrago S, Muñoz-Úbeda M, Almendro-Vedia VG, Sánchez-Camacho J, Maroto BL, Moreno F, Bañuelos J, García-Moreno I, López-Montero I*, de la Moya S*.

2022

Frontiers in Molecular Biosciences 9: 910936

Mitochondrial membrane models built from native lipid extracts: Interfacial and transport properties.

Schiaffarino O, Valdivieso González D, García-Pérez IM, Peñalva DA, Almendro-Vedia VG, Natale P*, López-Montero I*.

Frontiers in Cellular and Infection Microbiology 12: XXXX

Interspecies relationships between nosocomial pathogens associated to preterm infants and lactic acid bacteria in dual-species biofilms.

Jara J, Jurado R, Almendro-Vedia VG, López-Montero I, Fernández L, Rodríguez JM, Orgaz B.

Nanoscale 14: 8028-8040

Tunable gold nanorod/NAO conjugates for selective drug delivery in mitochondria-targeted cancer therapy.

González-Rubio S, Salgado C, Manzaneda-González V, Muñoz-Úbeda M, Ahijado-Guzmán R, Natale P, Almendro-Vedia VG, Junquera E, Osío Barcina J, Ferrer I, Guerrero-Martínez A*, Paz-Ares L*, López-Montero I*.

2021

Journal of Nanobiotechnology 19: 425

Transgene expression in mice of the Opa1 mitochondrial transmembrane protein through bicontinuous cubic lipoplexes containing gemini imidazolium surfactants.

Muñoz-Úbeda M, Semenzato M, Franco-Romero A, Junquera E, Aicart E, Scorrano L, López-Montero I*.

Archives of Biochemistry and Biophysics 708: 108939

How rotating ATP synthases can modulate membrane structure.

Almendro-Vedia VG, Natale P, Valdivieso González D, Lillo MP, Aragones JL, López-Montero I*.

Soft Materials 19: 346-358

In-silico modeling of early-stage biofilm formation.

Nie P, Alarcon F, López-Montero I, Orgaz B, Valeriani C, Ciamarra MP.

Frontiers in Microbiology 11: 588884

Self-Adaptation of Pseudomonas fluorescens Biofilms to Hydrodynamic Stress.

Jara J, Alarcón F, Monnappa AK, Ignacio Santos JI, Bianco V, Nie P, Ciamarra MP, Canales A, Dinis L, López-Montero I*, Valeriani C*, Orgaz B*.

2020

Nature 586: 287-291

Na+ controls hypoxic signalling by the mitochondrial respiratory chain.

Hernansanz-Agustín P, Choya-Foces C, Carregal-Romero S, Ramos E, Oliva T, Villa-Piña T, Moreno L, Izquierdo-Álvarez A, Cabrera-García JD, Cortés A, Lechuga-Vieco AV, Jadiya P, Navarro E, Parada E, Palomino-Antolín A, Tello D, Acín-Pérez R, Rodríguez-Aguilera JC, Navas P, Cogolludo A, López-Montero I, Martínez-del-Pozo A, Egea J, López MG, Elrod JW, Ruíz-Cabello J, Bogdanova A, Enríquez JA, Martínez-Ruiz A.

Biomolecules 10: 1085

The GDP-bound state of mitochondrial mfn1 induces membrane adhesion of apposing lipid vesicles through a cooperative binding mechanism.

Tolosa-Díaz A, Almendro-Vedia VG, Natale P, López-Montero I*.

Bioelectrochemistry 133: 107490

Potentiometric detection of ATP based on the transmembrane proton gradient generated by ATPase reconstituted on a gold electrode.

García-Molina G, Natale P, Valenzuela L, Alvarez-Malmagro J, Gutiérrez-Sánchez C, Iglesias-Juez A, López-Montero I, Vélez M, Pita M, De Lacey AL.

FEBS letters 594: 1132-1144

Liquid–liquid phase separation of the Golgi matrix protein GM130.

Rebane AA, Ziltener P, LaMonica LC, Bauer AH, Zheng H, López-Montero I, Pincet F, Rothman JE, Ernst AM.

Nanomaterials 10: 59

Intercellular trafficking of gold nanostars in uveal melanoma cells for plasmonic photothermal therapy.

Ahijado-Guzmán R, Sánchez-Arribas N, Martínez-Negro M, González-Rubio G, Santiago-Varela M, Pardo M, Piñeiro A, López-Montero I, Junquera E, Guerrero-Martínez A.

2019

Molecular Pharmaceutics 16: 4787-4796

Gemini-based lipoplexes complement the mitochondrial phenotype in MFN1-Knockout Fibroblasts.

Muñoz-Úbeda M, Tolosa-Díaz A, Bhattacharya S, Junquera E, Aicart E, Natale P, López-Montero I*.

Journal of Nanobiotechnology 17: 108-117

pH-triggered Endosomal Escape of Pore Forming Listerolysin O Toxin-coated Nanoparticles.

Plaza García-Abadillo I, Manzaneda V, Kisovec M, Almendro-Vedia V, Muñoz-Úbeda M, Guerrero-Martínez A, Anderluh G, Natale P*, López-Montero I*.

Journal of Nanobiotechnology 17:77

Lipid–peptide bioconjugation through pyridyl disulfide reaction chemistry and its application in cell targeting and drug delivery

de la Fuente-Herreruela D, Monnappa AK, Muñoz-Úbeda M, Morallón-Piña A, Enciso E, Sánchez L, Giusti F, Natale P, López-Montero I*

Physical Chemistry Chemical Physics 21, 13653-13667

Molecular dynamics study of nanoconfined TIP4P/2005 water: how confinement and temperature affect diffusion and viscosity.

Zaragoza A, Gonzalez MA, Joly L, López-Montero I, Canales A, Benavides AL, Valeriani C.

2018

Biochimica et Biophysica Acta (BBA)-General Subjects 1862: 2824-2834

Supramolecular zippers elicit interbilayer adhesion of membranes producing cell death.

Almendro-Vedia VG, García C, Ahijado-Guzmán R, de la Fuente-Herreruela D, Muñoz-Úbeda M, Natale P, Viñas MH, Queiroz Albuquerque R, Guerrero-Martínez A, Monroy F, Lillo MP, López-Montero I*.

ACS Applied Bio Materials 1: 1301-1310

Injectable hybrid hydrogels, with cell-responsive degradation, for tumor resection.

Alonci G, Fiorini F, Riva P, Monroy F, López-Montero I, Perretta S, De Cola L.

Frontiers in Oncology 8: 514

Enhanced cytotoxic activity of mitochondrial mechanical effectors in human lung carcinoma H520 cells: pharmaceutical implications for cancer therapy

González-Rubio S, Montero Pastor N, García C, Almendro-Vedia VG, Ferrer I, Natale P, Paz-Ares L, Lillo MP and López-Montero I*.

2017

BBA Bioenergetics 1858: 999-1006.

Rhodamine-based sensor for real-time imaging of mitochondrial ATP in living fibroblasts.

de la Fuente-Herreruela D, González-Charro V, Almendro-Vedia VG, Morán M, Martín MA, Lillo MP, Natale P, López-Montero I*.

Proc Natl Acad Sci U S A. 114: 11291-11296.

Non-equilibrium fluctuations of lipid membranes by the rotating motor protein F1F0 ATP synthase.

Almendro-Vedia VG, Natale P, Mell M, Bonneau S, Monroy M, Joubert F, López-Montero I*.

Adv Colloid Interface Sci. 247: 543-554.

Permeability modes in fluctuating lipid membranes with DNA-translocating pores.

Moleiro LH, Mell M, Bocanegra R, López-Montero I, Fouquet P, Hellweg T, Carrascosa JL, Monroy F.

Adv Colloid Interface Sci. 247: 514-520

Dissipative dynamics of fluid lipid membranes enriched in cholesterol.

Arriaga LR, Rodríguez-García R, Moleiro LH, Prévost S, López-Montero I, Hellweg T, Monroy F.

Adv Colloid Interface Sci. 247 Pages: 555-560.

The enzymatic sphingomyelin to ceramide conversion increases the shear membrane viscosity at the air-water interface.

Catapano ER, Natale P, Monroy F, López-Montero I*.

J. Chem. Educ, 94: 644–649

iGUVs: Preparing Giant Unilamellar Vesicles with a Smartphone and Lipids Easily Extracted from Chicken Eggs.

Almendro Vedia VG, Natale P, Chen S, Monroy F, Rosilio V, López-Montero I*.

J Am Chem Soc. doi: 10.1021/jacs.6b09485

Mechanosensitive Gold Colloidal Membranes mediated by Supramolecular Interfacial Self-Assembly.

Coelho JP, Mayoral MJ, Camacho L, Martín-Romero MT, Tardajos G, López-Montero I, Sanz E, Avila Brande D, Giner-Casares JJ, Fernández G, Guerrero-Martínez A.

Coll Surf B. 149: 174-183.

Nanomechanical properties of composite protein networks of erythroid membranes at lipid surfaces.

Encinar M, Casado S, Calzado-Martín A, Natale P, San Paulo A, Calleja M, Velez M, Monroy F, Lopez-Montero I*.

2016

ACS Omega 1: 388-395.

Intracellular pH-Induced Tip-to-Tip Assembly of Gold Nanorods for Enhanced Plasmonic Photothermal Therapy.

Ahijado-Guzmán R, González-Rubio G, Izquierdo JG, Bañares L, López-Montero I, Calzado-Martín A, Calleja M, Tardajos G, Guerrero-Martínez A.

Small 12: 4881-4893.

Nanocomposite Hydrogels as Platform for Cells Growth, Proliferation, and Chemotaxis.

Fiorini F, Prasetyanto EA, Taraballi F, Pandolfi L, Monroy F, López-Montero I, Tasciotti E, De Cola L.

Angew Chem Int Ed Engl 55: 6216-20.

H2 -Fueled ATP Synthesis on an Electrode: Mimicking Cellular Respiration.

Gutiérrez-Sanz Ó, Natale P, Márquez I, Marques MC, Zacarias S, Pita M, Pereira IA, López-Montero I*, De Lacey AL, Vélez M.

2015

Langmuir 31: 3912-3918.

Thermomechanical transitions of egg-ceramide monolayers.

Catapano ER, Lillo MP, García Rodríguez C, Natale P, Langevin D, Monroy F, López-Montero I*.

Biophys J. 108: 2794-2806.

Direct cytoskeleton forces cause membrane softening in red blood cells.

Rodriguez-Garcia R, López-Montero I, Mell M, Egea G, Gov N, Monroy F.

Chem Phys. Lipids. 185: 61-77.

Fluctuation dynamics of bilayer vesicles with intermonolayer sliding: Experiment and theory.

Mell M, Moleiro LH, Hertle Y, López-Montero I, Cao FJ, Fouquet P, Hellweg T, Monroy F.

2013

FASEB J 27: 3363-3375.

Intrinsic disorder of the bacterial cell division protein ZipA: coil-to- brush conformational transition.

López-Montero I, López-Navajas P, Mingorance J, Rivas G, Vélez M, Vicente M, Monroy F.

Eur Phys J E Soft Matter 36: 75.

Bending stiffness of biological membranes: What can be measured by neutron spin echo?

Mell M, Moleiro LH, Hertle Y, Fouquet P, Schweins R, López-Montero I, Hellweg T, Monroy F.

Langmuir 29: 6634 – 6644.

Shear and Compression Rheology of Langmuir Monolayers of Natural Ceramides: Solid Character and Plasticity.

López-Montero I, Catapano ER, Espinosa G, Arriaga LR, Langevin D, Monroy F.

Biochim Biophys Acta1828: 687-698.

Membrane reconstitution of FtsZ-ZipA complex inside giant spherical vesicles made of E. coli lipids: large membrane dilation and analysis of membrane plasticity.

López-Montero I*, P. López-Navajas, J. Mingorance, G. Rivas, M. Vélez, M. Vicente and F. Monroy.

2012

ACS Syn Biol 1: 414–424.

Efficient Orthogonal Integration of the Bacteriophage ϕ29 DNA-Portal Connector Protein in Engineered Lipid Bilayers.

Moleiro LH, López-Montero I, Márquez I, Moreno S, Vélez M, Carrascosa JL, Monroy F.

J Phys Chem Lett 3: 1583-1588.

Artificial spectrin shells reconstituted on giant vesicles.

López-Montero I*, Rodríguez-García R, Monroy F.

Biophys J 102: 2077-2085.

Accumulated bending energy elicits neutral sphingomyelinase activity in human red blood cells.

López DJ, Egido-Gabas M, López-Montero I, Busto JV, Casas J, Garnier M, Monroy F, Larijani B, Goñi FM, Alonso A.

Langmuir 28: 4744-4753.

Active membrane viscoelasticity by the bacterial FtsZ-division protein.

López-Montero I, Mateos-Gil P, Sferrazza M, Navajas PL, Rivas G, Vélez M, Monroy F.

2011

Biophys J 101: 2721-2730.

Solid character of membrane ceramides: a rheological study with their mixtures with sphingomyelin.

Catapano ER, Arriaga LR, Espinosa G, Monroy F, Langevin D, López-Montero I*

Biochem J 438: 555-564.

A combined action of pulmonary surfactant proteins SP-B and SP-C modulates permeability and dynamics of phospholipid membranes.

Parra E, Moleiro LH, López-Montero I, Cruz A, Monroy F, Pérez-Gil J.

EPL (Europhysics Letters) 94: 28009.

Subdiffusive fluctuation dynamics of rigid membranes as resolved by ultrafast video-microscopy.

Rodríguez-García R, Mell M, López-Montero I, Monroy F.

Soft Matter 7: 1532-1542.

Polymersomes: smart vesicles of tunable rigidity and permeability.

Rodríguez-García R, Mell M, López-Montero I, Netzel N, Hellweg T, Monroy F.

Soft Matter 7: 3100-3107.

Active membranes with bound F-actin: sliding vs. sticking conditions.

Isanta S, Espinosa G, Rodríguez-García R, Natale P, López-Montero I, Langevin D, Monroy F.

Proc Natl Acad Sci U S A, 108: 6008-6013.

Shear rheology of lipid monolayers and insights on membrane fluidity.

Espinosa G, López-Montero I, Monroy F, Langevin D.

2010

Biochim Biophys Acta 1798: 1348-1356

Ceramide: From lateral segregation to mechanical stress.

López-Montero I*, Monroy F, Vélez M, Devaux PF.

Chem Phys Lipids 163: 56-63

Lipid domains and mechanical plasticity of Escherichia coli lipid monolayers.

López-Montero I*, Arriaga LR, Rivas G, Vélez M, Monroy F.

J Phys Chem B 114: 4509-4520

Domain-Growth Kinetic Origin of Nonhorizontal Phase Coexistence Plateaux in Langmuir Monolayers: Compression Rigidity of a Raft-Like Lipid Distribution.

Arriaga LR, López-Montero I, Ignés-Mullol J, Monroy F.

Eur Phys J E Soft Matter 31: 105-113

Dissipative curvature fluctuations in bilayer vesicles: Coexistence of pure-bending and hybrid curvature-compression modes.

Arriaga LR, Rodríguez-García R, López-Montero I, Farago B, Hellweg T, Monroy F.

2009

Phys Rev Lett 102: 128101

Bimodal spectrum for the curvature fluctuations of bilayer vesicles: Pure bending plus hybrid curvature-dilation modes.

Rodríguez-García R, Arriaga LR, Mell M, Moleiro LH, López-Montero I, Monroy F.

Phys Rev E 80: 031908

Fluctuation dynamics of spherical vesicles: Frustration of regular bulk dissipation into subdiffusive relaxation.

Arriaga LR, López-Montero I, Orts-Gil G, Farago B, Hellweg T, Monroy F.

Biophys J 96: 3629-3637

Stiffening effect of cholesterol on disordered lipid phases: a combined NSE + DLS analysis of the bending elasticity of large unillamelar vesicles based on POPC.

Arriaga LR, López-Montero I, Monroy F, Orts-Gil G, Farago B, Hellweg T.

Mol Membr Biol 26: 194-204

Rapid transmembrane diffusion of ceramide and dihydroceramide spin-labeled analogues in the liquid ordered lamellar phase.

Pohl A, López-Montero I, Rouvière F, Giusti F, Devaux PF.

2008

Phys Rev E 77: 061918

Nonlinear dilational mechanics of Langmuir lipid monolayers: a lateral diffusion mechanism.

Arriaga LR, López-Montero I, Rodríguez-García R, Monroy F.

Langmuir 24: 4065-4076

High fluidity and soft elasticity of the inner membrane of Escherichia coli revealed by the surface rheology of model Langmuir monolayers.

López-Montero I, Arriaga LR, Monroy F, Rivas G, Tarazona P, Vélez M.

2007

J Biol Chem 282: 15559-15568

Flippase activity detected with unlabeled lipids by shape changes of giant unilamellar vesicles.

Papadopulos A, Vehring S, López-Montero I, Kutschenko L, Stöckl M, Devaux PF, Kozlov M, Pomorski T, Herrmann A.

Biochim Biophys Acta 1768: 553-561

Surface tension induced by sphingomyelin to ceramide conversion in lipid membranes.

López-Montero I, Vélez M, Devaux PF.

2006

2005

Chem Phys Lipids 141: 119-132

Proteins involved in lipid translocation in eukaryotic cells.

Devaux PF, López-Montero I, Bryde S.

J Biol Chem 280: 25811-25819

Rapid transbilayer movement of ceramides in phospholipid vesicles and in human erythrocytes.

López-Montero I, Rodriguez N, Cribier S, Pohl A, Vélez M, Devaux PF.